Boxwood – Buxus Sempervirens


Family: Buxaceae



Part Used:

Young Shoots

NOTE: These indications are only for use with embryonic plant stem cell tissues. Adult plants do not have the same constituents, actions or applications in most cases.

The Buxus sempervirens is a large, round, dense shrub with aromatic foliage to the ground. This ancient shrub, native to southern Europe, northern Africa, and western Asia, is slow growing and may reach as high as 15 feet. Its shiny, smelly evergreen leaves are elliptical to oblong, yellow-green beneath, and are no longer than an inch. Its slender, grooved twigs produce small buds and inconspicuous, yellow-, petal less flowers from May to June, followed by three-lobed, multiseeded fruit in September. The Buxus sempervirens is known for its capacity to fertilize and improve the soils on which it drops its leaves. It is also known for the extraordinary durability of its timber. The hard and heavy wood of the Buxus sempervirens has made it ideal for engraving, wood sculpting, and manufacturing instruments. Despite its potential for being poisonous, the plant has had wide medicinal use.

Boxwood trees can live up to six hundred years. In France, some were found to be more than four hundred years old. It is in leaf all year, slow growing and long lived, in flower from April to May, and the seeds ripen in September. The flowers are monoecious (individual flowers are either male or female, but both sexes can be found on the same plant) and are pollinated by bees and flies. It is noted for attracting wildlife.

The leaves have been used in France as a substitute for hops (Humulus lupulus) in making beer.

During the eighteenth century, boxwood was used to fertilize fields: "Looking for the worse field, if there is a boxwood tree, the soil underneath it will be rich, since the leaves fallen each year will have successively fertilized and improved it." (Departmental archives from Herault, Serie D, cote 181-1773).

During the fifteenth century, boxwood was used extensively for engraving and printing. It was also considered the best wood with which to carve molds since it can be finely sculpted, hence reproducing the minutest details.

Boxwood is slow growing but highly prized as it is twice as hard as oak. It can be cut into the finest patterns without breaking; sought after for making chess pieces & turned wood applications. And of course, the boxwood is the prime wood for wind instruments. In Virgil's time, Minerva recommended it for flutes. Perfume was once made from the bark. Leaves and sawdust were once used to dye hair auburn. Boxwood is as durable as brass and is used in instrument manufacture.

A tree that reaches beyond the dimensions known to mortal humans. Boxwood is an ancient tree on the evolutionary scale. It has been growing on the Earth for a long, long time, but it also has other timeless characteristics. Its leisurely slow growth, the extraordinary durability of its timber, its ability to stay green throughout the dead heart of winter, all seemed to indicate to our ancestors that here was a tree familiar with different dimensions, beyond those known to humans. The tree seemed almost impervious to injury. No matter how much it was pruned and clipped, it would continue to flourish and respond with an ever dense growth. Everyone knew that boxwood can be poisonous, yet it was undeniably a great medicine too.


Oligo-elements:

Fe, K, Mg, P, Si.


Phytochemical Constituents:

contain a volatile oil and alkaloids a butyraceous volatile oil and three alkaloids:
1. Buxine, the important constituent, chiefly responsible for the bitter taste and now regarded as identical with the Berberine of Nectander bark. One of the medicinally active chemicals present in all parts of the Boxwood is the steroid alkaloid 'buxine'. It is identical to the much better known 'berberine', present in Berberis vulgaris (Common Barberry), which is also poisonous taken in quantity. Berberine has anti-bacterial, anti-malarial and even some anti-viral action. It is also sedative and tends to lower blood pressure.
2. Parabuxine
3. Parabuxonidine, which turns turmeric paper deep red.
4. The bark contains chlorophyll, wax, resin, argotized tallow, gum, lignin, sulphates of Potassium and lime, carbonates of lime and magnesia, phosphates of lime, iron and silica."
5. Other sources (e.g. Schauenberg and Paris) report that the whole plant contains the steroid alkaloid buxine, as well as four secondary alkaloids and an essential oil.
The present study shows that the leaves of common Boxwood (Buxus sempervirens L.) accumulate red carotenoids (eschscholtzxanthin, monoanhydroeschscholtzxanthin, anhydroeschscholtzxanthin)

New triterpenoidal alkaloids from Buxus sempervirens
Two new triterpenoidal alkaloids,
(1) (+)-16a, 31-diacetylbuxadine
(2) (-)-Nb-demethylcyclomikuranine
(3) along with three known natural products, (-)-cyclomikuranine
(5) (-)-cyclobuxophylline-K
(5) (+)-buxaquamarine Isolated for the first time from this species of genus Buxus.
Compound 1 exhibited antibacterial activity against human pathogenic bacteria
Spirofornabuxine is an unusual alkaloid isolated from the eurasian shrub Buxus sempervirens. It is an excellent substitute for quinine. Boxwood was especially recommended for patients who do not respond well to quinine. Boxwood is a "Wonder drug' for the treatment of fevers.

Boxwood is able to maintain high CD4 levels over a sustained period of time despite episodic IV drug abuse and bouts of opportunistic infections. Contains five alkaloids. Antiviral, Antibacterial, Anticancer Oxytoxic, Antiparasitic. Inhibits Viral Replication in HIV- CFS & CFIDS, Smallpox, Fever, Malaria. Increases CD4 T-Cells and NK/Natural Killer Cells.


Other Phytochemical Constituents:

Auxins (IAA),Berberine,Brassinosteroids (BR),Cytokinins (CK), Florigen, Gibberellins (GA),Cycloprotobuxine, Isochondodendrine, Linoleic-Acid,Meristems plant stem cells (PSC), Oleic-Acid, Tannin.


Plant Stem Cell Therapy Indications:

Polycrest Immune Regulator!


Immunological System:

'P' Anticancer Oxytoxic. Increases CD4 T-Helper-Cells CD19 B-Cells and NK/Natural Killer Cells. Triterpenoid alkaloids all contributing an immunomodulating effect referred to as Host Defense Potentiators (HDP) and/or Biological Response Modifiers (BRM). Autoimmune diseases;Multiple Sclerosis, Cystic Fibrosis


Infectious Diseases:

'P' Antiviral, Antibacterial, Antiparasitic, Antimalarial, Inhibits Viral Replication in HIV, CFS & CFIDS, Smallpox, Malaria. Boxwood is a "Wonder drug' for the treatment of fevers.Isochondodendrine (type alkaloid) Antimalaria; Antiperiodic; Antileishmanic (Infections caused by protozoa of the genus Leishmania); Antitumor; Protisticide (Kills any member of the kingdom protista, a single-celled endo-organism). Isochondodendrine was found to have the most potent (antimalaria) activity. Plasmodium is a genus of parasitic protozoa.


GI – Digestive - Hepatology:

'P' Anti parasitic, Vermifuge, Intestinal Disinfectant, It stimulates gastric secretions and the flow of bile from the liver, Constipation, Diarrhea, Hemorrhoids. Cholinesterase-Inhibiting Triterpenoid Alkaloids from Buxus.


Hematology Oncology:

'A' antineoplastic activity.Studies with animals have shown CLA to reduce breast, prostate, stomach, colorectal, lung, and skin cancers. The CLA may slow the growth of cells that give rise to cancer. A human study has shown an association between linoleic acids and a decreased risk for prostate cancers.


Cardiovascular System:

'A' Mild hypotensive.


Ob Gyn/Reproductive System:

'A' Antiperiodic, Dysmenorrhea. Preeclampsia hypertension during pregnancy at small dosage.


Musculoskeletal System:

'A' Rheumatoid Arthritis, Osteoporosis in Immunodeficient patients, Facilitate the absorption of calcium.


Nervous System:

'A' Sedative due to eschscholtzxanthin which helps in Insomnia.


Dermatology:

'A' Hair loss, dandruff, opens sores that do not heal properly. Athlete’s foot soaks (1 TBSP in lukewarm water, soak 20 minutes).


Dental:

'A' Toothache.