Elm+–+Ulmus+Campestris

=Elm – Ulmus Campestris =  //**Family: Urticaceae**// 


 * 1 Part Used:
 * 2 Abstracts of Published Research on Elm – Ulmus Campestris
 * 3 Oligo-elements:
 * 4 Vitamins and Minerals:
 * 5 Phytochemical Constituents:
 * 6 Plant Stem Cell Therapy Indications
 * <span style="display: block; line-height: 1.5em; list-style-image: none; list-style-type: none; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0.3em; padding: 0px; text-align: left;"><span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; text-decoration: none;">7 Dermatology:
 * <span style="display: block; line-height: 1.5em; list-style-image: none; list-style-type: none; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0.3em; padding: 0px; text-align: left;"><span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; text-decoration: none;">8 Topical use for:
 * <span style="display: block; line-height: 1.5em; list-style-image: none; list-style-type: none; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0.3em; padding: 0px; text-align: left;"><span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; text-decoration: none;">9 Musculoskeletal System:
 * <span style="display: block; line-height: 1.5em; list-style-image: none; list-style-type: none; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0.3em; padding: 0px; text-align: left;"><span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; text-decoration: none;">10 GI – Digestive System:
 * <span style="display: block; line-height: 1.5em; list-style-image: none; list-style-type: none; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0.3em; padding: 0px; text-align: left;"><span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; text-decoration: none;">11 Ob Gyn:
 * <span style="display: block; line-height: 1.5em; list-style-image: none; list-style-type: none; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0.3em; padding: 0px; text-align: left;"><span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; text-decoration: none;">12 ENT:
 * <span style="display: block; line-height: 1.5em; list-style-image: none; list-style-type: none; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0.3em; padding: 0px; text-align: left;"><span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; text-decoration: none;">13 Neurological System:
 * <span style="display: block; line-height: 1.5em; list-style-image: none; list-style-type: none; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0.3em; padding: 0px; text-align: left;"><span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; text-decoration: none;">14 Endocrine System:
 * <span style="display: block; line-height: 1.5em; list-style-image: none; list-style-type: none; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0.3em; padding: 0px; text-align: left;"><span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; text-decoration: none;">15 Hematology – Oncology:
 * <span style="display: block; line-height: 1.5em; list-style-image: none; list-style-type: none; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0.3em; padding: 0px; text-align: left;"><span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; text-decoration: none;">16 Renal – Uro Genital System:

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Part Used: ** <span style="border-bottom-width: 0.8em; border-color: white; border-left-width: 1.4em; border-right-width: 0px; border-style: solid; border-top-width: 0.5em; clear: right; display: block; float: right; margin-bottom: 0.5em; width: auto;"><span style="background-color: #f9f9f9; border: 1px solid #cccccc; display: block; font-size: 12px; overflow-x: hidden; overflow-y: hidden; padding: 3px !important; text-align: center; width: 155px;">

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Buds

NOTE: //These indications are only for use with embryonic plant stem cell tissues. Adult plants do not have the same constituents, actions or applications in most cases.//

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">The //Ulmus campestris// is an especially large, deciduous tree that is found throughout the greater part of Europe, North Africa, Asia Minor, and Japan. The tree grows 60 to 100 feet high, often attaining a height of 120 feet and 40 to 50 feet in girth. This towering tree sends out numerous spreading branches, extending 30 to 40 feet from its trunk, on which multitudinous branchlets and twigs form a rounded top. Its oval-shaped, alternate leaves are rough-textured and double-toothed. They form a green, billowy mass upon its limbs, rendering it a classic shade tree.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Its insignificant, small reddish-green flowers, appearing before spring foliage, give way to winged seeds that mature in April-May. Its dark green, double-toothed leaves are 3 to 6 inches long, tough-textured, and are unequally lobed at the base. This tree’s corky, gray bark, scored by grand vertical furrows that mark its age with expanding rings of wood, characterize its ruggedness.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">The close-grained, knot-free wood of the Ulmus campestris render it especially useful in carpentry, including planks, blocks, dead eyes of rigging and ship’s pumps, coffins, wheels, furniture, wagons, carts, wheelbarrows, sheds, and farm structures. Its remarkable durability makes it especially useful for purposes that require water exposure. Prior to the use of cast-iron, this wood was very much in use for water pipes. Also, once seasoned, it does not crack. Edible uses include fruit and tea.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">**Phytosociology**: The drought-tolerant nature of this tree requires that it produce a lot of humus (a complex organic substance resulting from the breakdown of plant material in a process called humification). Humus is often described as the “life force” of the soil, which is analogous to the life force of the human body. This process can occur naturally in soil or in the production of compost. Humus is extremely important to the fertility of soils in both a physical and chemical sense.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Physically, it helps the soil retain moisture and encourages the formation of good soil structure. Chemically, it has many active sites which bind to ions of plant nutrients, making them more available. The abundance of humus, i.e., life force, produced by this tree, acts as a rehydrate and rejuvenator of the skin when taken in extract form.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">**Bach flower applications**: For the type of person who is naturally capable of coping with most personal and work commitments, but is inclined to feel overburdened with additional responsibility. The positive quality of this remedy is that of greater self-belief. These applications also apply to Plant Stem Cell Therapy.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Abstracts of Published Research on Elm – Ulmus Campestris: **

<span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em; text-decoration: none;">Phytochem Anal. 2009 Sep;20(5):395-401. Characterisation of phenolics in Flor-Essence--a compound herbal product and its contributing herbs//Saleem A, Walshe-Roussel B, Harris C, Asim M, Tamayo C, Sit S, Arnason JT// <span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">2.

<span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; color: #002bb8; line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em; text-decoration: none;">Biol Pharm Bull. 2008 Nov;31(11):2090-6. Antihypertensive, vasorelaxant, and antioxidant effect of root bark of Ulmus macrocarpa//Oh KS, Ryu SY, Oh BK, Seo HW, Kim YS, Lee BH//

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Oligo-elements: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Cu, Cr, Fe, I, K, Mg, Mn, P, Se, Si, Ti. Zn.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Vitamins and Minerals: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">A, B-1, B-2, B3, Calcium, E.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Phytochemical Constituents: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Ascorbic-Acid, Auxins (IAA), //**Beta-Sitosterol**//, Beta-Carotene, **Brassinosteroids (BR)**, //Caprylic acid//, //Decanoic acid// also known as //Capric acid//,**Cytokinins (CK)**, Flavonoids, //**Gibberellins (GA), Jasmonic acid (JA), Meristems plant stem cells (PSC), Salicylates (SA)**//, **Three Sesquiterpenes:** 2-Hydroxy-5-Isoproppyl-8-MEehtyl-5,6,7,8-Tetrahydro-3-Napth, 7-Hydroxycalamenal, 7-Hydroxycalmenene. Ascorbic-Acid, Beta-Sitosterol, Beta-Carotene, Caprylic acid, Decanoic acid also known as Capric acid, Flavonoids, Salicylic acid, Tannin, Ulmic Acid,**Ulmicin**, Ulmin. **Sesquiterpenes three guaiane type:**torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-hydroxytorilin A. All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells. Tannin, Ulmic Acid, Ulmicin, Ulmin.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">**A total of** //6 sesquiterpenes// **in Elm.**

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">**Sesquiterpenes** three guaiane type: torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-hydroxytorilin A. All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells. In the central nervous system microglia play a major role in the inflammatory process, and numerous activated microglia surround dopaminergic neurons in the substantia nigra (SN) of Parkinson's disease (PD) brains. Uncontrolled microglial activation may be directly toxic to neurons by releasing various substances such as nitric oxide (NO), prostaglandin E2, superoxide, and pro inflammatory cytokines such as interleukin-1β (IL-β), tumor necrosis factor-alpha, and interleukin-6. These molecules can induce dopaminergic neuron death, and inhibition of microglial activation can protect dopaminergic neurons.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Microglias are immune competent cells in the central nervous system. Guaiane Sesquiterpenes are antimicrobial-cytotoxic agent. Microglia are a type of glial cell that acts as the first and main form of active immune defense in the central nervous system (CNS). Microglia constitute 20% of the total glial cell population within the brain. Unlike astrocytes, individual microglia are distributed in large non-overlapping regions throughout the brain and spinal cord. Microglia are constantly moving and analyzing the CNS for damaged neurons, plaques, and infectious agents. The brain and spinal cord are considered “immune privileged” organs in that they are separated from the rest of the body by a series of endothelial**cells** known as the blood-brain barrier, which prevents most infections from reaching the vulnerable nervous tissue. In the case where infectious agents are directly introduced to the brain or cross the blood-brain barrier, **microglial cells** must react...

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Mucilage which is a combination of small and long-chain polysaccharides including hexoses, pentoses, methylpentoses, and polyuronides. Upon hydrolysis these carbohydrates yield galactose, glucose, fructose, galacturonic acid, l-rhamnose and d-galactose. Mucilage - Resembles that of flaxseed.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Mucilage of elm is a splendid demulcent for irritable and irritated or inflamed mucous membranes, and to relieve dryness of the tissues of the mouth and throat, and to alleviate cough. It is one of the best agents to use after poisoning by irritants, to allay the distress and protect the inflamed tissues.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">**Five new triterpene esters named ulmicin A-E (1-5):** <span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">1. 3beta,11alpha,15alpha-trihydroxylup-20(29)-ene-11-(3'-methoxy-4' hydroxybenzoyl ester). <span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">2. 3beta,11alpha,15alpha-trihydroxylup-20(29)-ene-11-(4'-hydroxybenzoyl ester). <span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">3. 3beta,11alpha,15alpha-trihydroxylup-20(29)-ene-11-(3'-methoxy-4'-hydroxybenzoyl)-15-(4'-hydroxybenzoyl ester). <span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">4. 3beta,11alpha,15alpha-trihydroxylup-20(29)-ene-11,15-di(3'-methoxy-4'-hydroxybenzoyl ester). <span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">5. 3beta,11alpha,15alpha-trihydroxylup-20(29)-ene-11-(3'-methoxy-4'-hydroxybenzoyl)-15-(benzoyl ester).

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">All five compounds showed significant neuroprotective activities against glutamate-induced neurotoxicity in primary cultures of rat cortical cells.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">**References: Author: Lee, M K : Kim, Y C. Citation: J-Nat-Prod. 2001 Mar; 64(3): 328-31** <span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Triterpenes exhibit pro- and anti-inflammatory properties depending on chemical structure and dose, and may be useful in modulating the immune response.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Plant Stem Cell Therapy Indication: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">//Wet Skin Ailment! Opposite effect of Cedar which is for dry skin.//

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Dermatology: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">'P' Anti-inflammatory, Antibacterial, Anti-fungal. Its main indication is for the skin it detoxifies in great depth, great for all types of Eczemas, Weeping Eczema, Exudate, Blistering, Acne, Abscesses, Boils, regulate the Seborrhea flux and for Herpes #1(simplex) & #2(genitals) expedite the time that it takes for the lesions to heal. Excellent in Diaper Rashes. Jock Itch. Ringworm. Impetigo, Dermatitis Herpetiformis (in Celiac Disease). Hyperhydrosis. General skin detoxifying agent. Contains **Sesquiterpenes** which helps To Alleviate Everything From Stomach Ulcers And Psoriasis To Nail Fungus. Highly effective as a topical wound-healer. Sunburn. . //**Hydroxycalamenene**// represents a key substance of wound reactions in non-infected lime trees.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Topical use for: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Wounds, burns, boils, yeast infections and other skin conditions.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Musculoskeletal System: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">'P' Re-mineralizing, Rheumatism, Psoriatic Arthritis.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** GI – Digestive System: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">'P' Antiinflammatory, Diarrhea, Yeast Infection, Gastritis, Hiatus Hernia, IBS, Dysbiosis, Dyspepsia, Esophagitis, Celiac Disease, Ulcerative Colitis, Crohn’s disease. Fermentation, Stomach Peptic Ulcers. Wasting syndrome, failing to thrive and weight loss. Puts a protective mucilaginous lining coating over the stomach and esophagus. Reduces hyper peristaltic via a nerve reflex action. It is one of the best agents to use after poisoning by irritants, to allay the distress and protect the inflamed tissues. Restores the endothelial cells.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Ob Gyn: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">'P' Leucorrhea, Vaginitis, Breast Yeast Infections, Candia Albican infections.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** ENT: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">'P' Mucilage of elm is a splendid demulcent for irritable and irritated or soothes inflamed mucous membranes in the mouth and throat. **Will heal the vocal chords from over exertion excellent for singers will also strengthen the vocal chords.** Gargle with 10 drops into ¼ cup lukewarm water 3 to 4 x a day last gargle should be swallowed to reach the lower part of the pharynx. If they are nodule on the vocal chords add embryonic Arnica Montana 3 drops 3-4 times per day to this gargle.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Neurological System: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">//Investigational// **Parkinson's disease, Amyotrophic Lateral Sclerosis, Alzheimer’s and Dementia.** Neuroprotection, involves inhibition of microglial activation and decreased expression and activity of inducible nitric oxide synthase (iNOS). Protect dopaminergic neurons against lipopolysaccharide LPS insult. This is potentially mediated via inhibition of p38 MAPK activity. In addition, the PI3K pathway actively participates in the negative regulation of LPS-induced NO production. It also suggests that PPAR-γ activation may involve differential regulation of p38 MAPK and of the PI3K/Akt pathway in the regulation of the inflammatory process.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">In the central nervous system microglia play a major role in the inflammatory process, and numerous activated microglia surround dopaminergic neurons in the substantia nigra (SN) of Parkinson's disease (PD) brains. Uncontrolled microglial activation may be directly toxic to neurons by releasing various substances such as nitric oxide (NO), prostaglandin E2, superoxide, and proinflammatory cytokines such as interleukin-1β (IL-β), tumor necrosis factor-alpha, and interleukin-6. These molecules can induce dopaminergic neuron death and inhibition of microglial activation can protect dopaminergic neurons. <span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Nitric oxide (NO) fulfils important functions during pregnancy and has a role in implantation, decidualization, vasodilatation and myometrial relaxation. However, at high concentrations, such as those that are produced in sepsis, NO has toxic effects as it is a free radical. Nitric oxide (NO) is an important messenger molecule in a variety of physiological systems. NO, a gas, is produced from L-arginine by different isoforms of nitric oxide synthase (NOS) and serves many normal physiologic purposes, such as promoting vasodilation of blood vessels and mediating communication between nervous system cells. Sesquiterpenes either stop the brain from expressing iNOS in the first place or inhibit iNOS from making its brain cell-killing molecules. “Recent findings indicate that nitric oxide (NO) over-production might be an important factor in the pathogenesis of sporadic amyotrophic lateral sclerosis (SALS).

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">Nitric oxide (NO) is an enzymatic product of nitric oxide synthase (NOS). NO has significant physiological functions and an increasing body of evidence suggests that NO pathways are implicated in a number of neurological disorders, including Alzheimer's disease (AD) and other neurodegenerative dementias.

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">//Five new identified triterpene esters named ulmicin A-E (1-5): **Neuroprotective activities against glutamate-induced neurotoxicity** of benefits in drugs and alcohol addictions. Methamphetamine (METH) and its derivative 3,4-methylenedioxymethamphetamine (MDMA; ecstasy).//

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Endocrine System: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">'A' Boost adrenal glands without raising cortisol. A //**Decanoic acid minimize severe hypoglycemia (low blood sugar) and its effects on long-term brain function.**//

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Hematology – Oncology: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">A 7-Hydroxycalmenene (sesquiterpene): a potent cytotoxic agent against human adenocarcinoma A 549. May be used in dendritic cells-based immunotherapy for cancer functional maturation of human monocyte-derived dendritic cells.

 <span style="background-attachment: scroll; background-clip: initial; background-color: transparent; background-image: none; background-origin: initial; background-position: 0% 0%; background-repeat: repeat repeat; border-bottom-color: initial; border-bottom-style: none; border-bottom-width: medium; color: black; font-size: 17px; margin-bottom: 0.3em; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0.17em; padding-top: 0.5em;">** Renal – Uro Genital System: **

<span style="line-height: 1.5em; margin-bottom: 0.5em; margin-left: 0px; margin-right: 0px; margin-top: 0.4em;">'A' Gout Reduces Uric Acid. Cystitis, UTI.